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Carter-Kent C, Zein NN, Feldstein AE (2008) Cytokines in the pathogenesis of fatty liver and disease progression to steatohepatitis: implications for treatment

Supports cellular housekeeping GLP1 signaling appears to support autophagy and reduce oxidative and inflammatory trash inside cells, helping protect tissues from protein buildup and DNA damage over time

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Therefore, -cell failure is considered to play a major role in the pathogenesis of the disease