(1997) Biochemistry 36 : 6437-6447 PubMed: 9174360 Search on PubMed DOI: Primary Citation Related Structures: 1GRT, 2GRT, 3GRT, 4GRT, 5GRT PubMed Abstract: Trypanosoma and Leishmania, pathogens responsible for diseases such as African sleeping sickness, Chagas' heart disease, or Oriental sore, are two of the very few genera that do not use the ubiquitous glutathione/glutathione reductase system to keep a stable cellular redox balance
Topical copper-peptide delivery has a documented limitation worth stating plainly: the skin barrier limits how much of a peptide reaches the dermis
Researchers designing multi-peptide protocols for skin regeneration research often use these complementary delivery characteristics to their advantage, applying GHK-Cu serum followed by a Matrixyl-containing moisturizer to maximize dermal exposure through sequential application
GSH is capable of scavenging ROS through Nrf2-mediated heme oxygenase-1 induction and enhancing M1-like macrophage polarization regulation, showing that GSH may be a useful strategy to increase the human defense system (Mittal et al., 2014
