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The minimal clinically important difference threshold for weight loss in adults was considered as 5 % weight loss (Reference Shi, Wang and Hao21) , equal to 45 kg (Reference Shi, Wang and Hao22)

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The key context for this comparison is that both compounds are strictly preclinical -- all claims about cognitive effects are based on animal models, and the translation of these findings to human cognition is uncertain

For the corresponding disulfide of strep-MBP-GRXC2, the midpoint redox potential was also found to range between 230 and 240 mV