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Plausible degradation pathways include: Serum aminopeptidases (cleaving from the N-terminus) Endopeptidases (internal bond cleavage) Hepatic uptake and degradation Renal clearance (though direct renal excretion of intact peptide of this size is typically limited) Whether BPC-157 generates active metabolites i.e., smaller peptide fragments that retain biological activity is not established in the public literature

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Figure 4 FMT treatment caused the alteration of sugar, fatty acid, polyamines, and phenolic and phenyl derivatives, including a significant increase in D-fructose, -carotene, norepinephrine, glutamic acid, carbamoyl phosphate, -linolenic acid, retinoyl b-glucuronide, phenylethylamine, methyl jasmonate, and ophthalmate levels, and a decrease in D-galactose, methylmalonic acid, putrescine, 4-acetamidobutanoic acid, isocitric acid, 2-aminoacrylic acid, L-alanine, D-mannose, and 4-hydroxybenzoic acid levels

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