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Regulatory decisions and large-scale clinical evidence are establishing the drug class as a multi-system therapeutic platform

A systematic review and meta-analysis of 12 randomized controlled trials (RCTs) involving 11 459 overweight or obese adults without diabetes demonstrated that GLP-1 receptor agonists significantly reduced body weight, alongside notable improvements in glycemic control, lipid levels, and blood pressure

[7] Why This Matters: The Safety Record The clearest argument for tightening the pathway is the safety data the FDA and manufacturers have collected over the past two years

I dont think its been done, hardly at all. This article is exclusive to STAT+ subscribers Unlock this article and get additional analysis of the technologies disrupting health care by subscribing to STAT+