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Hormonal factors also play a major role in where stubborn fat accumulates

The carnitine system and its implication in cancer cells metabolic plasticity The use of diet-derived or adipose tissue-released long-chain fatty acids as energy substrates requires about 25 different enzymes and transport proteins, which carry out fatty acids, import, them into mitochondria, and facilitate the -oxidation steps

The function of the intestinal mucosal barrier is closely associated with the regulation of TJ protein levels

Moreover, nanoparticle-based formulations can enhance B-cell activation and antibody production while facilitating targeted delivery to lymph nodes through lymphatic drainage, resulting in strong, long-lasting, and antigen-specific immunity [14]