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Molecular Biotechnology, 37 (1), 31-37

PubMed Stephens NG, Parsons A, Schofield PM, et al

Structure delivered a competitive profile for its investigational GLP-1 pill compared to Eli Lillys orforglipron and Novo Nordisks oral Wegovy, BMO Capital Markets wrote to investors, after the candidate elicited 16.3% weight loss after 44 weeks in a Phase 2 trial

In mouse and rat models, measuring levels of active GLP-1 provides valuable insight into metabolic regulation, gut hormone signaling, and the mechanisms underlying glucose tolerance and energy balance