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Recently, the impact on the gluco-insulinemic profile of different therapeutic approaches has also been investigated in patients affected by prolactinomas resistant to CAB conventional dose therapy to determine whether high-dose CAB therapy (i.e., 2 mg/week) and pituitary surgery could exert a similar metabolic impact in these patients (62)

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Fibroblast cell-culture studies have characterized proliferation, migration, collagen synthesis, and gene-expression endpoints