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Combined inflammation reduction potentially superior for chronic retinal diseases

(2) Mitochondrial dysfunction in DAAs and reactive astrocytes Impaired oxidative phosphorylation (OXPHOS) DAAs exhibit reduced mitochondrial respiratory chain activity, leading to decreased ATP production via OXPHOS

Additionally, any drug development for PWS will need to address the complexities of the syndrome, which includes not only hyperphagia and obesity but also developmental issues, psychiatric conditions, and endocrine disorders

[1] How Prednisolone May Affect Weight Loss on Wegovy Prednisolone can significantly counteract the weight loss effects of Wegovy through several physiological mechanisms