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An interesting therapeutic strategy is to induce arginine transporters (e.g., Slc7a2) in antitumor T cells, before their adoptive transfer to patients, enhancing their ability to compete for arginine in the TME, without the deleterious effects of arginine depletion for antitumor immunity [8]

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Other toxins like heavy metals, such as mercury from dental fillings, can impair conversion of T4 to T3. 22 High exposure to these toxins, coupled with impaired detoxification due to poor diet, nutrient depletion from chronic stress, and genetic factors, may give them the opportunity to disrupt thyroid function