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The finding was replicated by tirzepatide maker Eli Lilly, who carried out tests on the impact of mixing tirzepatide and B12 and released a statement underscoring that the clinical consequences of the new molecule are not known
Who Might Be a Good Candidate
Recommended starting dose: Discontinue other basal insulin and/or GLP-1 agonist before initiating Xultophy Patients nave to basal insulin or a GLP-1 agonist: starting dose is 10 units once daily Patients currently on basal insulin or a GLP-1 agonist: starting dose is 16 units once daily Maintenance: titrate dose up or down by 2 units once or twice weekly, depending on blood sugar goals Missed doses: resume dosing at the next scheduled dose
Poor sleep disrupts GLP-1 and appetite regulation , while circadian alignment restores hormonal balance and glucose control (Frontiers)
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