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For context, the broader class also includes the GIP/GLP-1 dual agonist tirzepatide, studied in SURMOUNT (NEJM 2022) and SURMOUNT-OSA (NEJM 2024), plus other GLP-1 receptor agonists like liraglutide and dulaglutide

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Previous studies looking at GLP-1 drugs and the brain have suggested that the drugs may slow the loss of volume in the parts of the brain required for planning, memory, emotion and sensory integration