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The published research literature has investigated: Gene expression modulation across hundreds of genes (documented in microarray studies) Collagen synthesis and skin remodeling Tissue protection through antioxidant and copper-dependent mechanisms Wound healing and dermatological research Various aging-related cellular processes The mechanisms don't overlap meaningfully

As people age or deal with stress, poor sleep, or unhealthy habits, NAD+ levels drop

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Tesamorelin produces a stronger and more sustained increase (~2030%), while Sermorelin produces a shorter, more moderate rise (~1015%), consistent with its pulsatile mechanism