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Lancet 373 , 125136 (2009)

Accessed 06/03/2024

Whereas the GLP-1R has been broadly found across most types of neuronal cells within the brain, spinal cord, and ganglion and peripheral nerve 1,89,91 , with GLP-1 agonsits enhancing neuronal phenotypic markers (e.g., augmenting choline acetyltransferase levels in cholinergic cells and TH levels in DAergic neurons 35,91 ), there is increasing evidence that astrocytes likewise express GLP-1Rs and that injury and neuroinflammation elevate their expression

558 Furthermore, another Phase II trial (B-Sure) evaluated the durability of bepirovirsens antiviral effect (NCT04954859)