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Where there is limited evidence, physicians are relying on their training and clinical knowledge to guide them

However, evidence suggests that the combinations effect is not additive

GSH is also involved as an antioxidant in the detoxification of products deriving from ROS-promoted oxidation of lipids such as malonyl dialdehyde and 4-hydroxy-2-nonenal, and probably many other products of ROS interaction with cellular components (Comporti, 1987)

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