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The secondary outcomes were the change of mean arterial blood pressure (delta MAP, %), the kinetics of arterial blood pressure, gap CO 2 , gap CO 2 /oxygen arteriovenous difference ratio, oxygen delivery (DO 2 ), oxygen consumption (VO 2 ), arterial lactate, hematocrit, sodium, and chloremia over a period of 60 min

These can be temporary signals of hormonal recalibration

Transcriptional Protein Sp1 Regulates LEDGF Transcription by Directly Interacting with its Cis-Elements in GC-Rich Region of TATA-Less Gene Promoter

Thus, overall, polysomnographic studies indicate greater sleep efficiency with DSIP administration, it has probably not major observed effect on short-term treatment of chronic insomnia