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Nutrition Context: Why the Bowl Is Only Part of It Its tempting to reduce enzymatic endogenous antioxidants for dogs nutrition to a checklist: Does the food have antioxidants? But endogenous enzymes are not simply added in. Theyre produced and regulated by the body, and they depend on overall nutritional adequacy, energy balance, and the presence of supportive compounds that help the system function smoothly (Jewell DE, 2024)

Since oxidation via a mixed disulfide does not require binding of GSH to the scaffold site, it is plausible that some class III GRXs might act through this mechanism

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