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Lima, G

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While its clinical performance suggests that dual incretin agonism may redefine treatment expectations, careful integration into clinical practice will require continued evaluation of long term outcomes, comparative effectiveness, and health system implications

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Birknes B

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Side Effect Profiles The most noticeable practical difference is that dual agonists like tirzepatide tend to cause slightly more gastrointestinal side effects than pure GLP-1 agonists

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