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Symptoms That Are Normal (No Need to Contact Provider) Mild to moderate nausea during weeks 4 through 8 is expected and does not require a provider call unless management strategies prove completely ineffective

Ethical and feasibility concerns also limit the design of such trialsfor instance, it may not be justifiable to randomize patients to specific agents solely to assess safety outcomes, especially when some newer agents offer established cardiovascular and renal benefits

and Gas through the digestive tract