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Week 1 experiment: Administer DSIP 3 hours before intended sleep Track time to fall asleep, sleep quality, morning alertness Note any grogginess or sleep disturbance Week 2 experiment: Administer DSIP 1.5 hours before intended sleep Track the same variables Compare results to week 1 Week 3 experiment: Administer DSIP 30-45 minutes before intended sleep Track and compare Identify which timing produced the best results Some users find their optimal timing changes over a cycle

Sources Sikirica V, et al

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Reconstitution Math: 5mg Vial Add 2.5mL of BAC water to a 5mg (5,000mcg) vial: 5,000mcg 2.5mL = 2,000mcg per mL On a standard U-100 insulin syringe (100 units = 1mL): 300mcg dose = 0.15mL = 15 units 250mcg dose = 0.125mL = 12.5 units 500mcg dose = 0.25mL = 25 units 1,000mcg dose = 0.5mL = 50 units Reconstitution Math: 2mg Vial Add 2mL of BAC water to a 2mg (2,000mcg) vial: 2,000mcg 2mL = 1,000mcg per mL On a U-100 insulin syringe: 300mcg dose = 0.3mL = 30 units 250mcg dose = 0.25mL = 25 units 200mcg dose = 0.2mL = 20 units Step-by-Step Reconstitution Process Gather and prep Wash hands thoroughly