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After several years of research, the group reached a product that met all the benchmarks set out at the start of the research

Many practitioners stack sermorelin with ipamorelin for synergistic pituitary stimulation rather than using sermorelin alone

Inhaled and topical formulations exist but represent niche applications with less standardized dosing evidence

Although these results hint at potential beyond-weight reproductive benefits (83), the extremely small sample size ( n = 28), open-label design, and lack of objective measurements for key biological intermediates (e.g., oocyte/embryo quality and endometrial receptivity), combined with controversies over the adequacy of the washout period, mean these conclusions should be viewed as exploratory rather than definitive