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Both injected on the same day at different sites

Acknowledgements This research was financially supported by the POS Salute 20142020 of the Italian Ministry of Health, under Trajectory 3 Regenerative, Predictive and Personalized Medicine, Action Line 3.1, within the project Integrated Health and Genetics System for Cardiovascular Diseases (SISAGEN-CARDIO) (local project code T3-AN-18)

Currently, compelling evidence indicates that caspase-8 is required to mediate extrinsic Fas/FasL-driven eryptosis in mature erythrocytes [130, 148]