Pioglitazone and vitamin E can be considered with improvement in MASH and stabilization of fibrosis, as suggested by some studies (10, 11)
In a competitive field with players like Eli Lilly, triple agonists could offer differentiated efficacy and open new possibilities for patients struggling with obesity and related metabolic conditions
Intracerebroventricular (ICV) infusion of native GLP-1 promotes not only a reduction in food intake and body weight, but also an increase in BAT thermogenesis induced by increased sympathetic nervous system (SNS) activity [6]
The main adverse events reported by male AAS users to SERMs (clomiphene and tamoxifen) were decreased libido and erectile dysfunction (24%), acne (21%), fatigue (19%), mood disorders (13%), visual disturbances (5%), arthralgia (4%), insomnia (4%), and hot flushes (2%)