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This approach demonstrates synergy with deformable liposomes or transfersomes, which can further navigate through the intercellular spaces of the partially removed stratum corneum, hence improving their delivery efficiency [281]

Recreational nitrous oxide-related myeloneuropathy in adolescents: a multicenter retrospective case series and systematic literature review

132 In addition, interim analysis from a small higher dose study using twice-weekly 300 mg atesidorsen for 13 weeks demonstrated results consistent with the Phase II trial outcomes (Antisense Therapeutic Ltd.)

This review will focus on recent findings describing how different pathological states compromise BBB integrity, discuss current potential therapeutic approaches that have been explored for improving BBB integrity and slowing neurodegenerative disease pathologies, and the recent findings in microbial mediated modulation of the BBB