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My goal was to be 110 lbs, and please remember I am 52, so this is a reasonable weight for my stature
Not only did their weight decrease, but they experienced lower fasting insulin levels and better HOMA-IR scores, indicating improved insulin sensitivity
This means the margin for error is smaller
However, since most of the Pdx1-Cre;Trp53 R172H ;Rb f/f mice develop insulinoma only at the age of over 180 days and those mice die within 2 weeks after presenting with hypoglycemia as previously reported 22 , it is challenging to employ a larger number of the mice to complete our comparative protocol between [ 18 F]FB(ePEG12)12-exendin-4 and [ 68 Ga]DOTATOC PET/CT scans
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