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Their clinical impact has since expanded dramatically due to their ability to induce sustained weight loss, improve insulin sensitivity, reduce systemic inflammation, and alter gut physiology

In an embodiment is a compound of Formula I, or a pharmaceutically acceptable salt thereof, wherein the fatty acid is conjugated with a linker, and the linker comprises one or more (2-[2-(2-Amino-ethoxy)-ethoxy]-acetyl) moieties, in combination with zero or one to four amino acids

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Most active individuals take between 1,000 and 2,000 mg per day