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In conclusion, GLP-1RAs may effectively improve the clinical symptoms of COPD patients, alleviate airflow limitation, airway damage, fibrosis, and remodeling, shorten the hospital stay, reduce the economic burden of patients, and reduce the occurrence of COPD-related complications, improve the long-term prognosis of patients, thus playing a therapeutic and preventive role for COPD patients, and may provide a new target for the prevention and treatment of COPD

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In mouse models of Alzheimers disease synthetic incretin hormones exerted neuroprotective effects, including reduced amyloid plaque load, reducing oxidative stress and the chronic inflammatory response in the brain, and enhancing neurogenesis (72, 73)