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At the crossroads of the cGAS-cGAMP-STING pathway and the DNA damage response: implications for cancer progression and treatment

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A 25-trial meta-analysis found an average loss of 3.7 kg ( 8 lbs) roughly 34 % of starting body weight over 852 weeks compared with placebo (PubMed 2024)

Kumar A, Joishy T, Das S, Kalita MC, Mukherjee AK, Khan MR (2022) A potential probiotic Lactobacillus plantarum JBC5 improves longevity and healthy aging by modulating antioxidative, innate immunity and serotonin-signaling pathways in Caenorhabditis elegans