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GLP-1 agonists also help to modulate chronic inflammation linked with obesity by suppressing proinflammatory cytokines such as TNF-, IL-6, and IL-1, improving endothelial function

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Quick Answer: Semaglutide has minimal direct drug interactions but may increase hypoglycemia risk when combined with insulin or sulfonylureas, and oral semaglutide can affect absorption of medications like levothyroxine

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