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Type 2 diabetes is a complex disease and the significant glucose control and weight loss achieved with once-weekly semaglutide compared with dulaglutide are encouraging, as more treatment options are needed. Safety Safety profiles were similar between patients given semaglutide and dulaglutide, and less than 10% of patients had to discontinue therapy prematurely due to adverse events across all treatment groups

Next, to showcase the therapeutic ability of the circadian rhythm sense-response system, we focused on obesity, a major health burden in the 21st century 45,46 , and selected GLP-1 47 as the effector molecule due to its well-established clinical efficacy 47

Selective laser sintering scaffold with hierarchical architecture and gradient composition for osteochondral repair in rabbits