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Inflamm Bowel Dis 19:265274 Palmns MSA, Cowan TE, Bomhof MR, Su J, Reimer RA, Vogel HJ, Hittel DS, Shearer J (2014) Low-dose aspartame consumption differentially affects gut microbiota-host metabolic interactions in the diet-induced obese rat

We also finalized that the procedures described by CPT code 0540T would be assigned status indicator S (Procedure or Service, Not Discounted when Multiple) and APC 5694 (Level 4 Drug Administration) from CY 2019 through CY 2024 and did not propose to change the APC assignment for CY 2025 when CPT code 0540T was replaced by CPT code 38228

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Upregulation of Antioxidant and Repair Genes: It increases the expression of genes responsible for DNA repair, antioxidant production (e.g., superoxide dismutase), and the synthesis of structural proteins like collagen and elastin