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The lack of standard diagnostic criteria for HT makes the diagnosis process subjective and does not cover the entire spectrum of the disease
Difficulty breathing, hives, or swelling of the face, lips, or throat may signal a severe allergic reaction and require immediate medical attention
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However, anecdotal reports from online forums cited in a 2025 systematic review included anxiety and panic attacks, depression and anhedonia, insomnia, heart palpitations, fatigue and weakness, and loss of appetite
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