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suggests that the increase may particularly occur during the first 2 hours of exposure, while longer windows may blend early peaks with later, lower-amplitude release

Fungal invasion typically initiates in the hyponychium, an area of low adhesion of the nail plate, and progresses along the longitudinal ridges of the nail bed, resulting in a linear appearance of the fungal infection.5 In onychoscopy, the most frequent finding is an irregular border pattern with spicules at the proximal margin of the onycholytic area

Stress can also heighten pain perception, making heartburn feel more intense

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