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But their introduction, in addition to the expanding number of indications for which they are used will increase demand, and thereby help drive down cost as more companies enter the market (Mallapaty)

They share a conserved active site at the beginning of helix 1 of the thioredoxin fold

Drug-Induced Pigmentation: Medicines can sometimes cause darkening of the lips and surrounding skin

Options may include low-dose prophylactic antibiotics, postcoital antibiotic prophylaxis for women with intercourse-related infections, or vaginal estrogen therapy for postmenopausal women