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It should also be mentioned how new ancillary therapies that have shown very favourable effects even in patients with HF are able to significantly reduce the LD required to maintain effective decongestion, as shown in the STEP-HF and STEP-HF-DM studies

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DOI: Published online: April 4, 2017 Department of Pathology, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea 1 Department of Neurosurgery, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea 2 Department of Radiology, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea 3 Department of Pathology, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea Corresponding Author Se Hoon Kim, MD Department of Pathology, Severance Hospital, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul 03722, Korea Tel: +82-2-2228-1764 Fax: +82-2-362-0860 E-mail: [email protected] *Sung-eun Choi and Yoon Jin Cha contributed equally to this work

The migrated cells were detected by a light microscope, and quantitative analysis of each image was performed using Image J software