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Experimental studies have examined how activation of GHS-R1a influences growth hormone physiology, insulin-like growth factor-1 (IGF-1) signaling, metabolic regulation, and cellular adaptation processes

Peptides derived from milk and bean proteins, which have been shown to inhibit the activity of DPP4 in vitro , were also found to have glycaemic effects in mice (Reference Tominaga, Yokota and Tanaka96,Reference Uchida, Ohshiba and Mogami97) as plasma glucose levels decreased after an OGTT

The growing overlap between metabolic dysfunction and neurodegenerative disease has opened a new field of investigation

Bastian et al., 1995)