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Key distinctions include: GHK-Cus advantage lies in its well-characterized sequence, reproducible gene expression profile, and dual action on both synthesis and degradation pathways

GHK-Cu inhibits its activation and thereby reduces the production of pro-inflammatory cytokines, chemokines, and adhesion molecules

European Journal of Radiology , 82 (11), e676679

Abbreviations AMPK AMP-activated protein kinase COX II Cytochrome c oxidase subunit II mtDNA Mitochondrial DNA NEFA Nonesterified fatty acid PCR Polymerase chain reaction PGC-1 Peroxisome proliferator-activated receptor- coactivator-1 RPE Rating of perceived exertion VAS visual analogue scale Additional file Footnotes Competing interests This study was supported in part by a research fund from the KOHJIN Life Sciences Company, Ltd