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Impact on hypertensive disorders of pregnancy (HDP) HDP are serious pregnancy complications that include chronic hypertension, gestational hypertension, preeclampsia/eclampsia, and preeclampsia superimposed on chronic hypertension (Reference Garovic, Dechend and Easterling98)

This reduction in circulating toxins leads to a corresponding decrease in the production of pro-inflammatory cytokines, such as TNF-, IL-1, and IL-6

Research suggests NAD+ levels can drop by roughly 50% between ages 20 and 60, while glutathione declines in parallel due to oxidative stress, toxin exposure, and reduced production

These may include nausea, diarrhoea, abdominal cramping, or indigestion