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A recent study employed single-molecule array (Simoa), an ultra-sensitive technology, to quantitate very low concentrations (picomolar to femtomolar) of -synuclein protofibrils (PFs) in CSF of PD patients and observed an increased concentration of -synuclein PFs in PD patients (von Euler Chelpin et al., 2020)

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Modifications like fatty acid side chains or amino acid substitutions help them bind to albumin and resist dipeptidyl peptidase-4 (DPP-4) degradation

Se usa a menudo cuando el objetivo principal es mejorar la disponibilidad general de carnitina para la -oxidacin