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and VKORC1*4 , 20%

N-acetyl cysteine is provided in a free form, meaning it is already in a single, readily usable form rather than bound within a protein

This is one reason daily microdosing is problematic from a practical standpoint

This oxidative stress is particularly damaging because of METHs effects on dopamine, which undergoes autoxidation, leading to the generation of dopamine quinones and ROS (Figure 1)