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Except for controlled-release medication, disintegration of a solid drug product usually occurs more rapidly than drug dissolution and permeation
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Researchers modeling repeat-dose experiments generally aim to reach steady-state concentrations after four to five half-lives of continuous administration
[PMC free article] [PubMed] [Google Scholar] 14.Zhang J., Ye Z.-W., Chen W., Culpepper J., Jiang H., Ball L.E., Mehrotra S., Blumental-Perry A., Tew K.D., Townsend D.M
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