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During initiation, hydrogen atom abstraction occurs predominantly at the bis-allylic positions (C11 between the two double bonds in linoleate) due to the relatively low bond dissociation energy (75-80 kcal/mol) compared to allylic (88 kcal/mol) or alkyl (101 kcal/mol) positions [5]

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Now that we've tackled the financial aspect, let's talk frequency

To assess drug release, we applied FITC-conjugated D-CuP hydrogel to the wounds and measured the fluorescence signal of the residual hydrogel at predetermined time intervals in darkness