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The effect of this synergistic treatment is ASS-dependent, and the activity of the enzymes mentioned above can be restored by transfection of ASS, eliminating the sensitivity of tumor cells to ADI-PEG20 combined with 5-FU treatment

La carenza grave di carnitina pu essere causa di diverse patologie tra cui: anemia , scarsa efficienza muscolare , affaticamento cronico, livelli alterati di grassi nel sangue e disturbi cardiaci quindi, importante garantire al nostro organismo livelli adeguati di questo prezioso amminoacido