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Melanotan II legal status Current legal status: Not FDA-approved Legal to buy as research chemical Legal to possess Gray area to use Concerns about safety (no long-term studies) Why it's controversial: Links to skin cancer concerns, permanent skin darkening, unknown long-term effects

Enhancement of Hypoxia-Induced tumor cell death in vitro and radiation therapy in vivo by use of small interfering RNA targeted to Hypoxia-Inducible Factor-1

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39,40 GSH and NAC effectively block the cytokine-induced production of virus and may extend the latency period of early infection