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Treated rats developed white nodules at the injection sites
Because AOD-9604 works peripherally on fat tissue through beta-3 adrenergic receptors without affecting central appetite pathways, there is no adaptation of hunger-regulating systems and therefore no rebound effect when stopping
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Moreover, the heterogeneity of cell products means that released secretomes differ in terms of differentiation potency and secretome profiles of subpopulations, as well as influences in on secretome by different pathophysiological microenvironments in vivo [119]
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