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There are several good options right now: semaglutide (Wegovy), a GLP-1 receptor agonist medication tirzepatide (Zepbound), a GLP-1/GIP medication liraglutide (Saxenda), a GLP-1 medication Several oral medications are also approved by the FDA for weight loss, including: semaglutide (oral Wegovy) orforglipron (Foundayo) phentermine (Suprenza) naltrexone-bupropion (Contrave) orlistat (Xenical/Alli) These are FDA-approved for adults who have a BMI of 30 or higher or a BMI of 27 along with a weight-related condition such as type 2 diabetes, hypertension, high cholesterol, obstructive sleep apnea, cardiovascular disease, or MASH (metabolic dysfunction-associated steatohepatitis, previously dubbed fatty liver)

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