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Standard reconstitution with bacteriostatic water alone often fails for these sequences because neutral water leaves the peptide near the pH where it aggregates

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While freezing doesnt chemically destroy benzyl alcohol, the freeze-thaw cycle can cause the preservative to separate from the water

Rana A, Ahmed M, Rub A, Akhter Y (2015) A tug-of-war between the host and the pathogen generates strategic hotspots for the development of novel therapeutic interventions against infectious diseases