Nevertheless, synthetic drugs are often associated with a higher risk of side effects, including severe adverse reactions, and tend to be more expensive (Table 1)
Vomiting is a reported side effect of Mounjaro, although its less common than nausea, with less than 1 in 10 (approximately 9%) of users reporting this side effect
Semaglutide works by mimicking the action of glucagon-like peptide 1 (GLP-1), a naturally occurring hormone that has the following effects: Stimulates insulin production to help regulate blood sugar Inhibits glucagon release, slowing the release of sugar into the blood, causing the body to burn more fat Slows gastric emptying to make you feel full longer Reduces appetite (because you feel full) Together, these effects can help you slow the conversion of sugar to fat, burn more fat, feel less hungry, and adhere to a healthy diet, all of which make managing weight and blood sugar easier
Participants experienced blood pressure drops, though the effect was more significant in those without diabetes and who took the medication for 50 to 100 weeks