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Lessons Making a definitive diagnosis of cancerous lesions of the spine from imaging alone is insufficient in cases of suspected nerve sheath lesions and requires a combination of biopsy, immunohistopathology, and genetic profiling for confirmation

As this enzyme catalyzes a reversible reaction between isocitrate and -ketoglutarate, the inverse reaction, so called the reductive carboxylation, could occur to maintain TCA cycle intermediates under mitochondria defects

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