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Harnessing the metabolic vulnerabilities of leukemia stem cells to eradicate acute myeloid leukemia

Now that you have finished this video you should check out the next video in the Cell Injury, Cell Death & Cancer sections which covers Amyloidosis.

Following irradiation, Bmi1+ cells can be activated to contribute to crypt regeneration and epithelial repopulation, partially compensating for the loss of Lgr5+ stem cells 27

Several papers describe upregulation of the vascular endothelial growth factor receptor 2 ( VEGFR2 ) pathway and downstream nitric oxide signalling the so-called VEGFR2-Akt-eNOS axis which researchers hypothesise underlies its reported influence on wound healing and blood-flow restoration at an injury site